Academic History
- B.S. Western Washington University
- Ph.D. University of Washington, Seattle
Interests
The relationship between histone modifications, chromatin structure and the control of gene expression using the protozoan Tetrahymena thermophila as a model system.
Selected Research and Publications
- Wiley, E.A., *Myers, T., *Parker, K., *Braun, T., Yao, M.-C . (2005). The class I histone deacetylase Thd1p affects nuclear integrity in Tetrahymena thermophila. Eukaryotic Cell 4: 981-990.
- Wiley, E.A., Mizzen, C., Allis, C.D . (2000). Isolation and characterization of in vivo modified histones and an activity gel assay for identification of histone acetyltransferases. Methods in Cell Biology: Tetrahymena thermophila. (James Forney and David Asai, eds.) Academic Press 62: 379-394.
- Wiley, E.A., Ohba, R., Yao, M.-C., Allis, C.D . (2000). Developmentally regulated Rpd3p homolog specific to the transcriptionally active macronucleus of vegetative Tetrahymena thermophila. Molecular and Cellular Biology 23: 8319-8328.
- Huang, H., Smothers, J.F., Wiley, E.A., Allis, C.D . (1999). A nonessential HP1-like protein affects starvation-induced assembly of condensed chromatin and gene expression in macronuclei of Tetrahymena thermophila. Molecular and Cellular Biology 19: 3624-3634.
- Huang, H., Wiley, E.A., Lending, C.R., Allis, C.D . (1998). An HP1-like protein is missing from transcriptionally silent micronuclei of Tetrahymena. Proceedings of the National Academy of Science 95: 13624-13629.